Rhinocerebral mucormycosis with cavernous sinus thrombosis: case report

Authors

  • Erwin González Maza Médico, Jefe de Departamento de Medicina Interna Hospital Pedro de Bethancourt, Antigua, Guatemala
  • Mylene Mejía Noguera Medica, Ejercicio Profesional Supervisado de Dermatologia. Hospital General San Juan de Dios, Guatemala
  • Mario Cardenas Médico, Jefe de Residentes de Dermatologia. Hospital Pedro de Bethancourt, Antigua, Guatemala
  • Herbert Hacobo Dubón
  • Carolina Castellanos Médica, Residente II. Medicina Interna Hospital Pedro de Bethancourt, Antigua, Guatemala
  • César Conde Pereira
  • Ana Elisa Suárez Médico, Jefe del área de Tuberculosis y Hongos del Departamento de Laboratorio Clínico del Hospital General San Juan de Dios, Guatemala
  • Ingrid Rosario Velásquez Lorenzo Médica, Residente de patología. Hospital General San juan de Dios, Guatemala.

Keywords:

mucormicosis, diabetes mellitus, zygomycetes, Rhizopus arrhizus

Abstract

Mucormycosis is a highly invasive fungal infection that has stood out in recent decades, especially in immunosuppressed patients or with serious underlying or concomitant diseases; such as diabetes mellitus, hematological neoplasms, thalassemias, transplants, liver cirrhosis, kidney failure, immunodeficiencies. These mycoses are caused by opportunistic fungi of the order Mucorales, mainly Rhizopus spp, Lichtheimia spp, Mucor spp and Rhizomucor spp. They present with various clinical manifestations, including: cutaneous, pulmonary, gastrointestinal and rhinocerebral. The latter, in our case, was produced by Rhizopus arrhizus (R. Oryzae). This fungus has a predilection for ketoacidotic diabetic patients. It has a global distribution of 90%. The key to treatment is immediate aggressive debridement along with high doses of intravenous Amphotericin B. The prognosis in these patients is very unfavorable. We present a case of a male patient with decompensated diabetes mellitus with the evolution of a progressive, aggressive and fatal mycosis.

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Published

17-10-2023

How to Cite

González Maza, E., Mejía Noguera, M., Cardenas, M., Hacobo Dubón, H., Castellanos, C., Conde Pereira, C., … Velásquez Lorenzo, I. R. (2023). Rhinocerebral mucormycosis with cavernous sinus thrombosis: case report. Belize Journal of Medicine, 8(1), 27–31. Retrieved from https://bjomed.org/index.php/bjm/article/view/184

Issue

Section

Case Reports