The central role of bridging veins in the pathogenesis of chronic subdural hematoma

Authors

DOI:

https://doi.org/10.61997/bjm.v15i1.496

Keywords:

Bridging veins, Venous sinus, Superior sagittal sinus, Chronic subdural hematoma

Abstract

Background: The prevalence of chronic subdural hematoma continues to increase and is expected to become the most common neurosurgical condition by 2030. Its origin has been associated with the rupture of bridging veins into the subdural space. Method: This review aims to systematise knowledge about the bridging veins to the superior sagittal sinus through a narrative literature review of articles in English and Spanish from 2012 to 2025. Results: The bridging veins to the superior sagittal sinus exhibit great anatomical and morphological variability. Three types of anatomical configurations are identified; long and tortuous veins rupture more easily, especially when they enter at a right angle. Conclusion: Physiological aging causes brain atrophy and loss of vein elasticity, predisposing to rupture due to multifactorial causes. They have a diverse angioarchitecture and play a central role in the origin of spontaneous and traumatic chronic subdural hematomas.

Downloads

Download data is not yet available.

References

Khan M, Subtain A, Joseph J, Bhatia S, Lakhani D. Chronic calcified subdural hematoma masquerading as hemorrhagic extra-axial mass: A case report and brief review of the literature. Radiol Case Rep. 2024; 20(3):1615–9. doi: 10.1016/j.radcr.2024.12.030 DOI: https://doi.org/10.1016/j.radcr.2024.12.030

Weber C, Ferdowssian K, Hecht N, Vajkoczy P, Wessels L, Mertens R. Burr hole evacuation of chronic subdural hematoma in general versus local anesthesia: a systematic review and meta-analysis. Acta Neurochir (Wien). 2025; 167(1):66. doi: 10.1007/s00701-025-06475-x DOI: https://doi.org/10.1007/s00701-025-06475-x

Wang Ch, Zhou K, , Chen J, Qian J, Zhou Ch, Deng X, et al. The drainage tube into the dural-outer membrane space during burr hole evacuation for chronic subdural hematoma. Novel case report of 2 patients. Medicine (Baltimore). 2025; 104(28):e43330. doi: 10.1097/MD.0000000000043330 DOI: https://doi.org/10.1097/MD.0000000000043330

Cheng W, Yang Q, Yuan X, Wu J. Analysis of risk factors for recurrence after middle meningeal artery embolization combined with burr hole drainage in patients with chronic subdural hematoma. Medicine (Baltimore). 2025; 104(43):e45116. doi: 10.1097/MD.0000000000045116 DOI: https://doi.org/10.1097/MD.0000000000045116

Wei W, Yang T, Liu X, Li L, Fan Y. Gliomagenesis following chronic subdural hematoma: A case report. Exp Ther Med. 2025; 30(1):139. doi: 10.3892/etm.2025.12889 DOI: https://doi.org/10.3892/etm.2025.12889

Colonna S, Lo Bue E, Pesaresi A, Dolci L, Gatto A, Ceroni L, et al. Impact of surgical timing on chronic subdural hematoma outcomes: novel insights from a multicenter study. Neurosurg Rev. 2025; 48(1):349. doi: 10.1007/s10143-025-03502-4 DOI: https://doi.org/10.1007/s10143-025-03502-4

Scerrati A, Mantovani G, Cavallo MA, Flacco ME, Zangrossi P, Eichner S, et al. Evaluation of clinical outcome and predictive factors for thromboembolism or hemorrhagic complications in patients treated for chronic subdural hematoma. A prospective observational study. Neurosurg Rev. 2025; 48(1):305. doi: 10.1007/s10143-025-03441-0 DOI: https://doi.org/10.1007/s10143-025-03441-0

Hamada H, Tajitsu K,Tokimura H, Kuroki Sh,Hiwatari T, Hanaya R. Factors Related to Recurrence and Complications after Percutaneous Subdural Tapping for Chronic Subdural Hematomas (Aoki Method):Clinical Experiences of 383 Patients with Chronic Subdural Hematomas. Neurol Med Chir (Tokyo). 2025; 65(6): 263-70. doi: 10.2176/jns-nmc.2024-0224 DOI: https://doi.org/10.2176/jns-nmc.2024-0224

Scheer M , Beuchel V, Mauer UM, Efinger K, Schulz Ch. Tranexamic acid vs. embolization of the meningeal artery as an adjunctive therapeutic regime to reduce the recurrence rate after surgical relief of chronic subdural hematomas (TABASCO) - a randomized controlled trial. Trials. 2025; 26(1):207. doi: 10.1186/s13063-025-08888-6 DOI: https://doi.org/10.1186/s13063-025-08888-6

Schack A, Olsen MG, Hansen JT, Magnussen A, Larsen IM, Jensen HR, et al. Intracranial pressure changes during early postoperative mobilization in patients with chronic subdural hematoma. Acta Neurochirurgica. 2025; 167(1):234. doi: 10.1007/s00701-025-06655-9 DOI: https://doi.org/10.1007/s00701-025-06655-9

Estrella López AS, Espin Jiménez NP, Montalvo Ramos PA, Castillo López GA. Endovascular Embolization for Chronic Subdural Hematomas: A Literature Review of the Current Evidence. Cureus. 2025; 17(3):e80898. doi: 10.7759/cureus.80898 DOI: https://doi.org/10.7759/cureus.80898

Lucio Parra LJ, Romo López AG. Diagnóstico y tratamiento del hematoma subdural crónico. Ciencia Latina Revista Científica Multidisciplinar. 2023; 7(1):9647-63. doi: 10.37811/cl_rcm.v7i1.5164 DOI: https://doi.org/10.37811/cl_rcm.v7i1.5164

Chen H, Colasurdo M, Malhotra A, Gandhi D, Bodanapally UK. Advances in chronic subdural hematoma and membrane imaging. Front Neurol. 2024; 15:1366238. doi: 10.3389/fneur.2024.1366238 DOI: https://doi.org/10.3389/fneur.2024.1366238

Kim KH, Lee Y. Medical Management of Chronic Subdural Hematoma. Korean J Neurotrauma. 2023; 19(3):288-97. doi: 10.13004/kjnt.2023.19.e47 DOI: https://doi.org/10.13004/kjnt.2023.19.e47

Mansour HM, Chaurasia B. Neovascularization in Outer Membrane of Chronic Subdural Hematoma : A Rationale for Middle Meningeal Artery Embolization. J Korean Neurosurg Soc. 2024; 67(2):146-57. doi: 10.3340/jkns.2023.0105 DOI: https://doi.org/10.3340/jkns.2023.0105

Shahid AH, Khaleghi M, Suggala S, Dyess G, Basett M, Butler DW, et al. Endoscopic subdural membranectomy formulti-septated chronic subdural hematoma: Finding a safe solution whenmiddle meningeal artery embolization is not feasible. Surg Neurol Int. 2025; 16:214. doi: 10.25259/SNI_340_2025 DOI: https://doi.org/10.25259/SNI_340_2025

Osuka K, Ohmichi Y, Ohmichi M, Honma S, Suzuki Ch, Aoyama M, et al. Membrane of Chronic Subdural Angiogenesis in the Outer Membrane of Chronic Subdural Hematomas through Thrombin-Cleaved Osteopontin and the Angiogenesis in the Outer. Biomedicines. 2023; 11(5):1440. doi: 10.3390/biomedicines11051440 DOI: https://doi.org/10.3390/biomedicines11051440

Mosquera Betancourt G, Téllez Isla R, Fuentes-Chávez J, Ramírez-Reyes E, Toledo Cabarcos Y. Caracterización tomográfica de las membranas en pacientes con hematoma subdural crónico. Arch Méd Camagüey. 2022; 26:e9184. Disponible en: http://scielo.sld.cu/pdf/amc/v26/1025-0255-amc-26-e9184.pdf

Mosquera Betancourt G, Téllez Isla R, Fuentes-Chávez J, Alfonso Gómez L, Brunet Bernal G. Caracterización macroscópica de las membranas de los hematomas subdurales crónicos. Rev Cubana Inv Bioméd. 2025; 44:e3720. Disponible en: https://revibiomedica.sld.cu/index.php/ibi/article/view/3720/1814.

Qiao Y, Alkarawi S, Provasek VE, Zhang YJ, Tsappidi S, Hui F. Chronic subdural hematoma: What precisely are we treating? Interv Neuroradiol. 2024; 21:15910199241263633. doi: 10.1177/15910199241263633 DOI: https://doi.org/10.1177/15910199241263633

Papageorgiou N, Palaiodimou L , Melanis K , Theodorou A, Stefanou MI, Tsalouchidou PE, et al. Embolization of Middle Meningeal Artery in Patients with Chronic Subdural Hematoma: A Systematic Review and Meta-Analysis of Randomized-Controlled Clinical Trials. J. Clin. Med. 2025; 14(9):2862. doi: 10.3390/jcm14092862. DOI: https://doi.org/10.3390/jcm14092862

Habibi MA, Alavi SA, Boskabadi AR, Seraj FQ, Mirjnani MS, Benam M, et al. Is It Safe to Use Tranexamic Acid for Chronic Subdural Hematoma: A Systematic Review and Meta-Analysis. Asian J Neurosurg. 2025; 20(2):219-28. doi: 10.1055/s-0044-1801771 DOI: https://doi.org/10.1055/s-0044-1801771

Kota N, Keshireddy A, Pruthi A, Abidin Z, Koneru M. A Scoping Review of the Methodologies and Reporting Standards in Recent Applications of Artificial Intelligence in Radiomics for Chronic Subdural Hematoma Imaging. Cureus. 2025; 17(2):e79163. doi: 10.7759/cureus.79163 DOI: https://doi.org/10.7759/cureus.79163

Yagi K, Hijikata Y, Tao Y, Sunada Y, Haruta R, Maruno M. Contralateral Progression after Unilateral Surgery for Bilateral Chronic Subdural Hematoma: A Prospective Observational Study. Neurol Med Chir. (Tokyo). 2025; 65(4):195-202. doi: 10.2176/jns-nmc.2024-0308 DOI: https://doi.org/10.2176/jns-nmc.2024-0308

Yamada SM, Tomita Y, Iwamoto N, Nishimura S. Incision of the Internal Membrane Under an Endoscope for Advanced Organized Chronic Subdural Hematoma: A Case Report. Cureus. 2025; 17(4):e83213. doi: 10.7759/cureus.83213 DOI: https://doi.org/10.7759/cureus.83213

Foppen M, Slot KM, Vandertop WP, Verbaan D. Timing of surgery for chronic subdural hematoma in patients with mild to moderate symptoms: a retrospective cohort study. Acta Neurochir (Wien). 2025; 167(1):147. doi: 10.1007/s00701-025-06552-1 DOI: https://doi.org/10.1007/s00701-025-06552-1

Mortazavi MM, Denning M, Yalcin B, Shoja MM, Loukas M, Tubbs S. The intracraneal bridging veins: a comprenhensive review of their history, anatomy, histology, pathology and neurosurgical implications. Childs Nerv Syst. 2013; 29:1073-78. doi: 10.1007/s00381-013-2054-3 DOI: https://doi.org/10.1007/s00381-013-2054-3

Hiramatsu M, Ozaki T, Tanove S, Mizutani K, Nakamura H, Tokuyama K. Detailed anatomy of bridging veins around foramen magnum: a multicenter stydy using tridimensional angiography. Clin Neuroradiol. 2024; 34(1):67-74. doi: 10.1007/s00062-023-01327-6 DOI: https://doi.org/10.1007/s00062-023-01327-6

Sadler TW. Embriología Médica de Langman. 14th Ed. Wolters Kluwer Health; 2019.

Standring S (ed). Gray's Anatomy: The Anatomical Basis of Clinical Practice. 42nd Ed. Elsevier; 2021.

Mantovani G, Scerrati A. The Cerebral Venous System: New Pathophysiological Theories and Diseases Related to Veins Occlusion [Internet]. Cerebral Circulation - Updates on Models, Diagnostics and Treatments of Related Diseases. IntechOpen; 2022. doi: 10.5772/intechopen.102351 DOI: https://doi.org/10.5772/intechopen.102351

Baltsavias G, Paterno V, Lanfermann H. The So-Called Cranial Dural Channels and Their Relationship with the Bridging Veins. AJNR Am J Neuroradiol. 2021; 42(4):E29-E30. doi: 10.3174/ajnr.A6972 DOI: https://doi.org/10.3174/ajnr.A6972

Migueis GFJ, Fernandes FAO, Ptak M, Ratajczak M, Alves de Sousa RJ. Detection of bridging veins rupture and subdural haematoma onset using a finite element head model. Clin Biomech (Bristol). 2019; 63:104-111. doi: 10.1016/j.clinbiomech.2019.02.010 DOI: https://doi.org/10.1016/j.clinbiomech.2019.02.010

Ota T. Functional cerebral venous anatomy from the view point of venous colaterales. Supratentorial, superficial and deep venous system. Stroke Vasc Interv Neurol. 2024; 4:e001050. doi: 10.1161/SVIN.123.001060 DOI: https://doi.org/10.1161/SVIN.123.001050

Brannigan J, McClanahan A, Hui F, Fargen KM, Pinter N, Oxley TJ. Superior cortical venous anatomy for endovascular device inmplantation: a systemic review. J NeuroIntervent Surg. 2024;16(12):1353-9. doi: 10.1136/jnis-2023-021434 DOI: https://doi.org/10.1136/jnis-2023-021434

Agarwal N, Carare RO. Cerebral Vessels: An Overview of Anatomy, Physiology, and Role in the Drainage of Fluids and Solutes. Front Neurol. 2021; 11:611485. doi: 10.3389/fneur.2020.611485 DOI: https://doi.org/10.3389/fneur.2020.611485

Karatas D, Martínez Santos JL, Uygur S, Dagtekin A, Kurtoglu Olgunus Z, Avci E, et al. A new classification of parasagittal bridging veins based on their configurations and drainage routes pertinent to interhemispheric approaches: a surgical anatomical study. J Neurosurg. 2023; 140(1):271-81. doi: 10.3171/2023.4.JNS222866 DOI: https://doi.org/10.3171/2023.4.JNS222866

Chesire E, Harris N, Malcomson R, Amoroso JM, Moreton JE, Biggs MJ. Macroscopic and histological examination of human bridging veins. Forensic Sci Int. 2024; 361: 112080. doi: 10.1016/j.forsciint.2024.112080. DOI: https://doi.org/10.1016/j.forsciint.2024.112080

Ye Y, Lan T, Zeng X, Yang J, Wei R, Zhu J, et al. Bridging veins: an analysis of surgical anatomy and histology correlated with interhemispheric approaches. Front Neuroanat. 2024; 18:1406252. doi: 10.3389/fnana.2024.1406252 DOI: https://doi.org/10.3389/fnana.2024.1406252

Shapiro M, Raz E, Nossek E, Srivatanakul K, Young M, Narayan V, Ali A, Sharashidze V, Esparza R, Nelson PK. Cerebral venous anatomy: implications for the neurointerventionalist. J Neurointerv Surg. 2023; 15(5):452-60. doi: 10.1136/neurintsurg-2022-018917 DOI: https://doi.org/10.1136/neurintsurg-2022-018917

Bateman GA, Bateman AR, Lechner-Scott J. Dilatation of the bridging cerebral veins in multiple sclerosis correlates with fatigue and suggests an increase in pressure. Mult Scler Relat Disord. 2023; 76:104843. doi: 10.1016/j.msard.2023.104843 DOI: https://doi.org/10.1016/j.msard.2023.104843

Famaey N. Cui ZY, Musigazi GU, Ivens J, Depreitere B, Verbeken E, et al. Structural and mechanical characteristization of bridging veins: A review. J Mech Behav Biomed Mater. 2015; 41:222-40. doi: 10.1016/j.jmbbm.2014.06.009 DOI: https://doi.org/10.1016/j.jmbbm.2014.06.009

Zhu Y, Wang F, Deng X. Hemodynamics of cerebral bridging veins connecting the superior sagittal sinus based on numerical simulation. Biomed Eng Online. 2018; 17(1):35. doi: 10.1186/s12938-018-0466-8 DOI: https://doi.org/10.1186/s12938-018-0466-8

Folgueira A, Acuña M. Senos durales [Internet]. 2019. Laboratorio de Neuroanatomía. Facultad de Medicina, Universidad de Buenos Aires. Disponible en: https://fmed.uba.ar/sites/default/files/2019-01/Senos%20venosos_0.pdf

García-Vilana S, Sánchez-Molina D. Age effects on the mechanical behavior of human cerebral bridging veins. Clin Biomech (Bristol). 2022; 100:105792. doi: 10.1016/j.clinbiomech.2022.105792 DOI: https://doi.org/10.1016/j.clinbiomech.2022.105792

Zhou Z, Li X, Kleiven S. Biomechanics of Acute Subdural Hematoma in the Elderly: A Fluid-Structure Interaction Study. J Neurotrauma. 2019; 36(13):2099-108. doi: 10.1089/neu.2018.6143 DOI: https://doi.org/10.1089/neu.2018.6143

Familiari P, LapollaP, Relucenti M, Battaglione E,Cristiano L, Sorrentino V, et al. Cortical atrophy in chronic subdural hematoma from ultra‑structures to physical properties. Sci Reps. 2023; 13:3400. Disponible en: 10.1038/s41598-023-30135-8. DOI: https://doi.org/10.1038/s41598-023-30135-8

Vargas Sanabria M. Abordaje del trauma cráneo encefálico en patología forense. Med leg Costa Rica. 2014; 31(2). Disponible en: https://www.scielo.sa.cr/pdf/mlcr/v31n2/art07v31n2.pdf

Gavrila RA, Kapeliotis M, Famey N, Depreitere BKleiven S, Vander J. Quantifying biovariability in position and diameter of bridging veins to improve acute subdural hematoma prediction in FE head models. In: Proceedings of Science [Internet]. Sissa Medialab Srl; 2022. p. 337–52. Disponible en: https://www.ircobi.org/wordpress/downloads/irc21/pdf-files/2141.pdf

Monea AG, Baeck K, Verbeken E, Verpoest I, Sloten JV, Goffin J, et al. The biomechanical behaviour of the bridging vein-superior sagittal sinus complex with implications for the mechanopathology of acute subdural haematoma. J Mech Behav Biomed Mater. 2014; 32:155-65. doi: 10.1016/j.jmbbm.2013.12.007 DOI: https://doi.org/10.1016/j.jmbbm.2013.12.007

Downloads

Published

15-01-2026

How to Cite

Mosquera Betancourt, G., Serrano González, L. M., Téllez Isla, R., Alfonso Gómez, L., & Brunet Bernal, G. (2026). The central role of bridging veins in the pathogenesis of chronic subdural hematoma. Belize Journal of Medicine, 15(1). https://doi.org/10.61997/bjm.v15i1.496