Probiotic Saccharomyces boulardii CNCM I-745: from research to clinical practice

Authors

  • Carlos Castañeda-Guillot Profesor Principal Titular y Analista de Investigación. Facultad de Ciencias Médicas. Universidad Regional Autónoma de Los Andes ̶ UNIANDES ̶ Ambato, Tungurahua, Ecuador

DOI:

https://doi.org/10.61997/bjm.v6i2.144

Keywords:

Saccharomyces boulardii CNCM I-745, probiotics, pharmacodynamics, pharmacokinetics

Abstract

An update on the unique yeast with probiotic action Saccharomyces boulardii CNCM I-745 is presented from research to clinical
practice, following the principles of evidence-based medicine due to the results achieved in clinical trials and meta-analyzes. The
characteristics of its pharmacodynamics and pharmacokinetics are reviewed. Its mechanisms of action are detailed based on research carried out in vitro, in animals and humans. The indications for its clinical use in different intestinal diseases with special reference to acute infectious gastroenteritis and its prevention, antibiotic associated diarrhea, recurrent diarrhea by Clostridium difficile and its prevention and other intestinal disorders such as dysbiosis, irritable colon and traveler's diarrhea are shown. Reference is made to its safety and adverse effects. The advantages of the only probiotic yeast regarding bacterial probiotics are established.

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Published

17-10-2023

How to Cite

Castañeda-Guillot, C. (2023). Probiotic Saccharomyces boulardii CNCM I-745: from research to clinical practice. Belize Journal of Medicine, 6(2), 15–21. https://doi.org/10.61997/bjm.v6i2.144

Issue

Vol. 6 No. 2 (2017): July-December

Section

Review

License

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