Characterization of patients with hypertensive disease of pregnancy at the Southern Regional Hospital, Belize, 2022




hypertensive disorders of pregnancy, ethnicity, maternal complications, fetal complications


Introduction: Of the 10% of women, who suffer from hypertension during pregnancy worldwide; between 2-8% constitute preeclampsia. The implications for maternal morbidity and mortality, given the high prevalence and incidence of hypertensive disorders in southern Belize, motivated this study. Objective: To characterize patients with hypertensive disorders of pregnancy at the Southern Regional Hospital, during the year 2022. Methods: A descriptive, retrospective study was carried out. The universe consisted of all pregnant patients admitted to the obstetrics-gynecology service of the aforementioned institution, and a sample of 89 patients who presented hypertensive disorders of pregnancy was taken. Results: Hypertensive disorders in pregnancy were more frequent in nulliparous women between 21 and 30 years of age. The Mayan ethnic group was the most affected. The study identified an incidence of 7.5%. Severe preeclampsia from hypertensive disease is shown with 47.1%; it was associated with low weight (24.7%) and prematurity (19.10%), with Intrauterine Growth Restriction being the most frequent fetal complication. The most common maternal complication was liver disorder. The maternal death rate was 171x10,000 live births. Conclusions: Improving preconception and prenatal care is essential to prevent the appearance of hypertensive disorders of pregnancy and reduce the high morbidity and mortality associated with this condition.


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Bartal MF, Sibai BM. Gestational hypertension, preeclampsia and eclampsia. En: Spong CY, Lockwood CJ, editores. Queenan's Management of High-Risk Pregnancy: An Evidence‐Based Approach. 7ma ed. Londres: Wiley Online Library; 2023. p. 101-113. doi: DOI:

Khan B, Allah Yar R, Khakwani AK, Karim S, Arslan Ali H. Preeclampsia Incidence and Its Maternal and Neonatal Outcomes With Associated Risk Factors. Cureus. 2022; 14(11):e31143. doi: DOI:

Cabrera Lozada C, Gómez J, Faneite P, Uzcátegui O. Mortalidad materna por trastornos hipertensivos del embarazo. ¿Es inevitable? Maternidad “Concepción Palacios” 1939-2020. Gac Méd Caracas. 2021; 129(3):585-97. Disponible en: DOI:

Serruya SJ, de Mucio B, Sosa C, Colomar M, Duran P, Gomez Ponce de Leon R, et al. Surveillance of severe maternal morbidity and maternal mortality in maternity hospitals of the Latin American and Caribbean network - Red CLAP: study protocol. Glob Health Action. 2023; 16(1):2249771. doi: DOI:

Alkema L, Chou D, Hogan D, Zhang S, Moller AB, Gemmill A, et al. Global, regional, and national levels and trends in maternal mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Maternal Mortality Estimation Inter-Agency Group. Lancet. 2016; 387(10017):462-74. doi: DOI:

Organización Mundial de la Salud, Fondo Internacional de Emergencia de las Naciones Unidas para la Infancia, Grupo del Banco Mundial, División de Población de las Naciones Unidas. Tendencias en la Mortalidad Materna de 2000 a 2017. Ginebra (Suiza):OMS [Internet]; 2019. Disponible en:

Sinkey RG, Battarbee AN, Bello NA, Ives CW, Oparil S, Tita ATN. Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of International Guidelines. Curr Hypertens Rep. 2020; 22(9):66. doi: DOI:

Sheen JJ, Huang Y, Andrikopoulou M, Wright JD, Goffman D, D'Alton ME, et al. Maternal age and preeclampsia outcomes during delivery hospitalizations. Am J Perinatol. 2020; 37(1):44-52. doi: DOI:

Amarán Valverde JE, Sosa Zamora M, Pérez Pérez M, Arias Acosta D, Valverde Bravo I. Principales características de la preeclampsia grave en gestantes ingresadas en un hospital de Zimbabwe. Medisan. 2009; 13(3). Disponible en:

Khedagi AM, Bello NA. Hypertensive Disorders of Pregnancy. Cardiol Clin. 2021; 39(1):77-90. doi: 10.1016/j.ccl.2020.09.005

Rogne T, Gill D, Liew Z, Shi X, Stensrud VH, Nilsen TIL, et al. Mediating factors in the association of maternal educational level with pregnancy outcomes: a Mendelian Randomization Study. JAMA Netw Open. 2024; 7(1):e2351166. doi: DOI:

Organización Mundial de la Salud. Recomendaciones de la OMS para la

prevención y el tratamiento de la preeclampsia y la eclampsia. Ediciones de la OMS: Ginebra; 2014. Disponible en:

Khedagi AM, Bello NA. Hypertensive Disorders of Pregnancy. Cardiol

Clin. 2021; 39(1):77-90. doi: DOI:

Flores Loayza ER, Rojas López FA, Valencia Cuevas DJ, De la Cruz Vargas JA, Correa López LE. Preeclampsia y sus principales factores de riesgo. Rev Fac Med Hum. 2021; 17(2): 90–99. doi: DOI:

Tyrmi JS, Kaartokallio T, Lokki AI, Jääskeläinen T, Kortelainen E, Ruotsalainen S, et al. Genetic risk factors associated with preeclampsia and hypertensive disorders of pregnancy. JAMA Cardiol. 2023; 8(7):674-683. doi: DOI:

Sathiya R, Rajendran J, Sumathi S. COVID-19 and Preeclampsia: Overlapping Features in Pregnancy. Rambam Maimonides Med J. 2022; 13(1):e0007. doi: DOI:

Cagino KA, Trotter RD, Lambert KE, Kumar SC, Sibai BM. Expectant management of preeclampsia with severe features diagnosed at less than 24 weeks. Am J Obstet Gynecol. 2024: S0002-9378(24)00557-X. doi: DOI:

Churchill D, Duley L, Thornton JG, Jones L. Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks’gestation. Cochrane Database Syst Rev. 2013; (7):CD003106. doi: DOI:

Ramos Filho FL, Antunes CMF. Hypertensive Disorders: Prevalence, Perinatal Outcomes and Cesarean Section Rates in Pregnant Women Hospitalized for Delivery. Rev Bras Ginecol Obstet. 2020; 42(11):690-696. doi: DOI:

Jaber S, Jauk VC, Cozzi GD, Sanjanwala AR, Becker DA, Harper LM, et al. Quantifying the additional maternal morbidity in women with preeclampsia with severe features in whom immediate delivery is recommended. Am J Obstet Gynecol MFM. 2022; 4(3):100565. doi: DOI:

Organización Panamericana de la Salud, Organización Mundial de la Salud. Salud en las Américas. Perfil de país: Belice [Internet]. 2023. Disponible en:

Aracil Moreno I, Rodríguez-Benitez P, Ruiz-Minaya M, Bernal Claverol M, Ortega Abad V, Hernández Martin C, et al. Maternal Perinatal Characteristics in Patients with Severe Preeclampsia: A Case-Control Nested Cohort Study. Int J Environ Res Public Health. 2021; 18(22):11783. doi: DOI:

Loor-Cedeño LA, Pincay-Cardona LD, Yumbo-Santana YS, Reyna-Valdiviezo GD, Villacreses-Cantos KL, Delgado-Molina JB. Preeclamsia y complicaciones materno fetales. Pol Con. 2021; 6(2):101-9. Disponible en:

Tropea T, Mavichak W, Evangelinos A, Brennan-Richardson C, Cottrell EC, Myers JE, Johnstone ED, Brownbill P. Fetoplacental vascular effects of maternal adrenergic antihypertensive and cardioprotective medications in pregnancy. J Hypertens. 2023 Nov 1;41(11):1675-1687. doi: 10.1097/HJH.0000000000003532 DOI:



How to Cite

Rodríguez Duarte, L. A., Martínez Frometa, L. E., & Parham, S. (2024). Characterization of patients with hypertensive disease of pregnancy at the Southern Regional Hospital, Belize, 2022. Belize Journal of Medicine, 13(2).