Retinopathy of prematurity in patients admitted to the Neonatal Intensive Care Unit at Karl Heusner Memorial Hospital
DOI:
https://doi.org/10.61997/bjm.v13iSuppl1.467Keywords:
Retinopaty of prematurity, Low birth weight, BelizeAbstract
Introduction: Retinopathy of prematurity is an ocular disease that can affect primarily premature and very low birth weight newborns. Active screening of newborns with these risk factors is performed at the Neonatal Intensive Care Unit of the Karl Heusner Hospital in Belize. Objective: To describe clinical and epidemiological factors in premature neonates screened for retinopathy. Methods: A descriptive, retrospective study was conducted in 47 neonates identified as being at risk for retinopathy of prematurity, over a period of six months, in the Neonatology Service of the Karl Heusner Memorial Hospital in Belize. Results: 36.2% of the neonates screened had some degree of retinopathy of prematurity. 82.3% of patients with a gestational age of less than 32 weeks developed retinopathy; similarly, 13 out of 17 newborns diagnosed had less than 1500 grams of birth weight. 60% of the patients with bronchopulmonary dysplasia and 40% of those who underwent mechanical ventilation, also had retinopathy. Oxygen therapy, especially prolonged and used with high-flow devices, was associated with both greater frequency and greater severity of retinopathy. Conclusions: Reducing prematurity and controlling risk factors are the main preventive measures for retinopathy of prematurity. Considering the frequency of this problem, it is necessary to create the conditions for carrying out treatment with any of its methods in the country.
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Bacalari MA, Schade R. Retinopatía del prematuro: Actualización en la detección y tratamiento. Rev Chil Pediatr. 2020; 91(1):120-30. doi: 10.32641/rchped.v91i1.1079 DOI: https://doi.org/10.32641/rchped.v91i1.1079
Guevara-Suta SE, Narvaes-Rumie OM, Gutiérrez AR, López- Cruz RL, Sánchez Rojas MC, Guacaneme-Ariza LN, et al. Oxígeno como factor asociado a retinopatía del prematuro en una unidad neonatal de Bogotá, Colombia. Pediatr. 2023; 56(3):e398. doi: https://doi.org/10.14295/rp.v56i3.398 DOI: https://doi.org/10.14295/rp.v56i3.398
Tejeda Palacios P. Retinopatía de la prematuridad. ¿Qué debe saber el pediatra? An Pediatr Continuada. 2014; 12(1):10-16. doi: 10.1016/S1696-2818(14)70161-1 DOI: https://doi.org/10.1016/S1696-2818(14)70161-1
Blencowe H, Lawn JE, Vazquez T, Fielder A, Gilbert C. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatr Res. 2013; 74(suppl 1):35-49. doi: 10.1038/pr.2013.205 DOI: https://doi.org/10.1038/pr.2013.205
Azad R, Gilbert C, Gangwe AB, Zhao P, Wu WC, Sarbajna P, et al. Retinopathy of Prematurity: How to Prevent the Third Epidemics in Developing Countries. Asia Pac J Ophthalmol (Phila). 2020; 9(5):440-8. doi: 10.1097/APO.0000000000000313 DOI: https://doi.org/10.1097/APO.0000000000000313
International Committee for the Classification of Retinopathy of Prematurity. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol. 2005; 123(7):991-9. doi: 10.1001/archopht.123.7.991 DOI: https://doi.org/10.1001/archopht.123.7.991
Chiang MF, Quinn GE, Fielder AR, Ostmo SR, Paul Chan RV, Berrocal A, et al. International Classification of Retinopathy of Prematurity, Third Edition. Ophthalmology. 2021; 128(10):e51-e68. doi: 10.1016/j.ophtha.2021.05.031
Jing J, Dai Y, Li Y, Zhou P, Li X, Mei J, et al. Single-course antenatal corticosteroids is related to faster growth in very-low-birth-weight infant. BMC Pregnancy Childbirth. 2021; 21(1):50. doi: 10.1186/s12884-020-03510-w DOI: https://doi.org/10.1186/s12884-020-03510-w
González CR, Díaz CM, Garretón CR. Anti-factor del crecimiento vascular endotelial (anti-VEGF) comparado con fotocoagulación láser para el tratamiento de la retinopatía del prematuro tipo 1. Medwave. 2022; 22(1):e8507. doi: 10.5867/medwave.2022.01.8507 DOI: https://doi.org/10.5867/medwave.2022.01.8507
Kaempfen S, Neumann RP, Jost K, Schulzke SM. Beta-blockers for prevention and treatment of retinopathy of prematurity in preterm infants. Cochrane Database Syst Rev. 2018; 3(3):CD011893. doi: 10.1002/14651858.CD011893.pub2 DOI: https://doi.org/10.1002/14651858.CD011893.pub2
Lloyd T, Isenberg S, Lambert SR. Current management of retinopathy of prematurity in sub-Saharan Africa. J AAPOS. 2020; 24(3):151.e1–151.e6. doi: 10.1016/j.jaapos.2020.03.002 DOI: https://doi.org/10.1016/j.jaapos.2020.03.002
Chiang MF, Quinn GE, Fielder AR, Ostmo SR, Paul Chan RV, Berrocal A, et al. International Classification of Retinopathy of Prematurity, Third Edition. Ophthalmology. 2021; 128(10):e51-e68. doi: 10.1016/j.ophtha.2021.05.031
Yu CW, Popovic MM, Dhoot AS, Arjmand P, Muni RH, Tehrani NN, et al. Demographic Risk Factors of Retinopathy of Prematurity: A Systematic Review of Population-Based Studies. Neonatology. 2022; 119(2):151-163. doi: 10.1159/000519635 DOI: https://doi.org/10.1159/000519635
Groth SL, Donahue SP. Epidemiology of Retinopathy of Prematurity in the US From 2003 to 2019. JAMA Ophthalmol. 2023; 141(11):1089-1090. doi: 10.1001/jamaophthalmol.2023.4613 DOI: https://doi.org/10.1001/jamaophthalmol.2023.4613
Mora JS, Waite C, Gilbert CE, Breidenstein B, Sloper JJ, Mora JS. A worldwide survey of retinopathy of prematurity screening. Br J Ophthalmol. 2018; 102:9-13. doi: 10.1136/bjophthalmol-2017-310709 DOI: https://doi.org/10.1136/bjophthalmol-2017-310709
Ochoa Araujo DA, Flores Peredo V, Romero Martínez JT, Martínez Rodríguez NL, Medina Contreras O. Incidencia y factores de riesgo de retinopatía del prematuro en el Hospital Regional Lic. Adolfo Lopez Mateo, ISSSTE. Rev Mex Oftalmol. 2019; 93(6). doi: 10.24875/rmo.m19000090 DOI: https://doi.org/10.24875/RMOE.M19000088
Berrocal AM, Fan KC, Al-Khersan H, Negron CI, Murray T. Retinopathy of Prematurity: Advances in the Screening and Treatment of Retinopathy of Prematurity Using a Single Center Approach. Am J Ophthalmol. 2022; 233:189-215. doi: 10.1016/j.ajo.2021.07.016 DOI: https://doi.org/10.1016/j.ajo.2021.07.016
Dani C, Coviello C, Panin F, Frosini S, Costa S, Purcaro V, et al. Incidence and risk factors of retinopathy of prematurity in an Italian cohort of preterm infants. Ital J Pediatr. 2021; 47(1):64. doi: 10.1186/s13052-021-01011-w DOI: https://doi.org/10.1186/s13052-021-01011-w
Lei C, Duan J, Ge G, Zhang M. Association between neonatal hyperglycemia and retinopathy of prematurity: a meta-analysis. Eur J Pediatr. 2021; 180(12):3433-42. doi: 10.1007/s00431-021-04140-w DOI: https://doi.org/10.1007/s00431-021-04140-w
Bonafiglia E, Gusson E, Longo R, Ficial B, Tisato MG, Rossignoli S, et al. Early and late onset sepsis and retinopathy of prematurity in a cohort of preterm infants. Sci Rep. 2022; 12(1):11675. doi: 10.1038/s41598-022-15804-4 DOI: https://doi.org/10.1038/s41598-022-15804-4
Strube YNJ, Wright KW. Pathophysiology of retinopathy of prematurity. Saudi J Ophthalmol. 2022; 36(3):239-242. doi: 10.4103/sjopt.sjopt_18_22 DOI: https://doi.org/10.4103/sjopt.sjopt_18_22
de Las Rivas Ramírez N, Luque Aranda G, Rius Díaz F, Pérez Frías FJ, Sánchez Tamayo T. Risk factors associated with Retinopathy of Prematurity development and progression. Sci Rep. 2022; 12(1):21977. doi: 10.1038/s41598-022-26229-4 DOI: https://doi.org/10.1038/s41598-022-26229-4
Vinekar A, Rao SV, Murthy S, Jayadev C, Dogra MR, Verma A, Shetty B. A Novel, Low-Cost, Wide-Field, Infant Retinal Camera, "Neo": Technical and Safety Report for the Use on Premature Infants. Transl Vis Sci Technol. 2019; 8(2):2. doi: 10.1167/tvst.8.2.2 DOI: https://doi.org/10.1167/tvst.8.2.2
Scruggs BA, Chan RVP, Kalpathy-Cramer J, Chiang MF, Campbell JP. Artificial Intelligence in Retinopathy of Prematurity Diagnosis. Transl Vis Sci Technol. 2020; 9(2):5. doi: 10.1167/tvst.9.2.5 DOI: https://doi.org/10.1167/tvst.9.2.5
Chiang MF, Quinn GE, Fielder AR, Ostmo SR, Paul Chan RV, Berrocal A, et al. International Classification of Retinopathy of Prematurity, Third Edition. Ophthalmology. 2021; 128(10):e51-e68. doi: 10.1016/j.ophtha.2021.05.031 DOI: https://doi.org/10.1016/j.ophtha.2021.05.031
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